The 2010–11 Louisville Cardinals men's basketball team represented the University of Louisville during the 2010–11 NCAA Division I men's basketball season, Louisville's 97th season of intercollegiate competition. The Cardinals competed in the Big East Conference and were coached by Rick Pitino, who was in his 10th season. The team played its home games on Denny Crum Court at the KFC Yum! Center, their first season at the new arena after 54 years at Freedom Hall.