Frank Annunzio (January 12, 1915 – April 8, 2001) was an American politician from Chicago, Illinois. Annunzio, an Italian-American, was born in Chicago, where he remained for his entire childhood and much of his adult life. He attended Crane Technical High School and DePaul University. He then had careers as a high school teacher and labor leader of the United Steelworkers of America. Under governor Adlai Stevenson II, he served as the state's Secretary of Labor from 1949 to 1952.