James William Trimble (February 3, 1894 – March 10, 1972) was a Democratic member of the United States House of Representatives from Arkansas, having served from 1945 to 1967. He was the first Democrat in Arkansas since Reconstruction to lose a congressional race to a Republican. Trimble was unseated in the 1966 general election by state GOP chairman John Paul Hammerschmidt of Harrison in Boone County, who won election on the ticket headed by gubernatorial nominee Winthrop Rockefeller.