Deep Blue Sea is a 1999 American science fiction horror film directed by Renny Harlin. It stars Saffron Burrows, Thomas Jane, Samuel L. Jackson, Michael Rapaport, and LL Cool J. Set in an isolated underwater facility, the film follows a team of scientists and their research on mako sharks to help fight Alzheimer's disease. The situation plunges into chaos when multiple genetically engineered sharks go on a rampage and flood the facility.