The Coquille River /koʊˈkiːl/ is a stream, about 36 miles (58 km) long, in southwestern Oregon in the United States. It drains a mountainous area of 1,059 square miles (2,740 km2) of the Southern Oregon Coast Range into the Pacific Ocean. Its watershed is between that of the Coos River to the north and the Rogue River to the south.