Charles F. Blair Jr. (July 19, 1909 – September 2, 1978) was an American aviation pioneer who helped work out the routes and navigation techniques necessary for long-distance flights. He served as a reserve officer, early in his career for the United States Navy, reaching the rank of captain, and later for the United States Air Force, reaching the rank of brigadier general. He died in a transportation accident in the Caribbean while captaining a Grumman Goose seaplane for his airline, Antilles Air Boats.