Wayne Grubb (born c. 1938) is a former American football and baseball coach. He served as the head football coach at Samford University in Homewood, Alabama from 1969 to 1973 and the University of North Alabama in Florence, Alabama from 1977 to 1987, compiling a career college football coaching record of 109–53–9. Grubb was also the head baseball coach at Samford in 1968.