USS Roe (DD-418) was a World War II-era Sims-class destroyer in the service of the United States Navy, named after Rear Admiral Francis Asbury Roe. Roe was laid down on 23 April 1938 by the Charleston Navy Yard; launched on 21 June 1939; sponsored by Mrs. Eleanor Roe Hilton; and commissioned on 5 January 1940, Lieutenant Commander in command.