The second USS La Salle (LPD-3/AGF-3) was built as a Raleigh-class amphibious transport dock and entered service with the United States Navy in 1964. La Salle was named for the city in Illinois that was in turn named after René-Robert Cavelier, Sieur de La Salle. La Salle saw service in the Caribbean Sea, Gulf of Mexico and throughout international waters in the Middle East. The vessel served as a command ship for . In 2005 the ship was decommissioned and sunk as a target ship off the Atlantic coast of the United States in 2007.