St. Paulus Lutheran Church was a historic church located at 999 Eddy Street in San Francisco, California. The church was built from 1892 to 1894 and was located next to Jefferson Square Park. It was added to the National Register of Historic Places in 1982. On October 5, 1980, the church became San Francisco Designated Landmark, number 116. The church's designated landmark status was rescinded after the church was destroyed by fire on November 5, 1995.