Simisola Olayemi Onibuwe Johnson (1929 – 2000) was a Nigerian dentist and gender advocate who served as Minister for Social Development and Culture during the nation's second republic. She was a former chairman of Allied Bank and the Lagos State branch of National Council of Women Societies. Johnson and Grace Guobadia both qualified as dentists in 1957, making both women the first set of trained female dentists in the country. She was a fellow of the National Postgraduate Medical College of Nigeria.