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About: Phenotypic screening     Goto   Sponge   NotDistinct   Permalink

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Type: yago:Abstraction100002137yago:Act100030358yago:Activity100407535yago:Event100029378yago:Experiment100639556yago:Investigation100633864yago:PsychologicalFeature100023100yago:Research100636921yago:WikicatGeneticsExperimentsyago:Work100575741yago:YagoPermanentlyLocatedEntitytelevision showyago:ScientificResearch100641820 New Facet based on Instances of this Class

Phenotypic screening is a type of screening used in biological research and drug discovery to identify substances such as small molecules, peptides, or RNAi that alter the phenotype of a cell or an organism in a desired manner. Phenotypic screening must be followed up with identification (sometimes referred to as target deconvolution) and validation, often through the use of chemoproteomics, to identify the mechanisms through which a phenotypic hit works.