Middlesex East was a former federal electoral district in Ontario, Canada, represented in the House of Commons of Canada from 1867 to 1968. It was created by the British North America Act of 1867, which divided the County of Middlesex into three ridings: Middlesex North, Middlesex West and Middlesex East. In 1882, the East Riding of the county of Middlesex it was defined as consisting of the townships of London, West Nissouri, North Dorchester and , the town of London East and the villages of London West and Springfield.