Henry Lee Moore (born 1874 in Boone County, Missouri — unknown) was an American forger, murderer and suspected serial killer who was convicted of killing his mother and grandmother with an axe in their home. While in prison, it was alleged by a Justice Department agent named W. M. McClaughry that Moore was possibly responsible for a string of unsolved axe murders in several states, among them being the Villisca axe Murders.