George Richard Piktuzis (January 3, 1932 – November 28, 1993) was an American professional baseball player, a left-handed pitcher who appeared as a relief pitcher in two games for the 1956 Chicago Cubs of Major League Baseball. The native of Chicago batted right-handed, stood 6 feet 2 inches (1.88 m) tall and weighed 200 pounds (91 kg). George Piktuzis died in Long Beach, California, at the age of 61.