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Désiré, Baron Collen (born in Sint-Truiden, Belgium, 21 June 1943) is a Belgian physician, chemist, biotechnology entrepreneur and life science investor. He made several discoveries in thrombosis, haemostasis and vascular biology in many of which serendipity played a significant role. His main achievement has been his role in the development of tissue-type plasminogen activator (t-PA) from a laboratory concept to a life-saving drug for dissolving blood clots causing acute myocardial infarction or acute ischemic stroke. Recombinant t-PA was produced and marketed by Genentech Inc as Activase and by Boehringer Ingelheim GmbH as Actilyse, and is considered biotechnology's first life saving drug.

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  • Désiré Collen (en)
  • Désiré Collen (de)
  • Désiré Collen (nl)
  • Désiré Collen (pt)
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  • Désiré Collen (Sint-Truiden, 21 de junho de 1943) é um médico, químico, empresário de biotecnologia e investidor belga. Collen fez várias descobertas em trombose, hemostasia e biologia vascular em muitas das quais teve um papel significativo. Sua principal conquista foi seu papel no desenvolvimento do ativador do plasminogênio do tipo tecido (t-PA), de um conceito de laboratório para um medicamento que salva vidas para dissolver coágulos sanguíneos, que causam infarto agudo do miocárdio ou acidente vascular cerebral (AVC). (pt)
  • Désiré, Baron Collen (born in Sint-Truiden, Belgium, 21 June 1943) is a Belgian physician, chemist, biotechnology entrepreneur and life science investor. He made several discoveries in thrombosis, haemostasis and vascular biology in many of which serendipity played a significant role. His main achievement has been his role in the development of tissue-type plasminogen activator (t-PA) from a laboratory concept to a life-saving drug for dissolving blood clots causing acute myocardial infarction or acute ischemic stroke. Recombinant t-PA was produced and marketed by Genentech Inc as Activase and by Boehringer Ingelheim GmbH as Actilyse, and is considered biotechnology's first life saving drug. (en)
  • Désiré Collen (* 21. Juni 1943 in Sint-Truiden) ist ein belgischer Mediziner und Molekularbiologe. Collen wurde 1968 an der Katholischen Universität Löwen in Medizin und 1974 in Chemie promoviert. Er wurde Professor an der Katholischen Universität Löwen, an der er seit 2002 Professor am Zentrum für vaskuläre und molekulare Biologie ist. Er leitet auch die Abteilung Transgene-Technologie und Gentherapie am Flämischen Institut für Biotechnologie. Er war an über 650 Publikationen beteiligt und an über 20 Patenten. (de)
  • Désiré baron Collen (Sint-Truiden, 21 juni 1943) is een Belgisch arts, chemicus en biotech-ondernemer. Hij deed uiteenlopende ontdekkingen op het vlak van trombose, hemostase en vasculaire biologie. Hij verwierf vooral bekendheid vanwege zijn rol in de ontwikkeling van recombinant t-PA (rt-PA) van een laboratoriumconcept tot een levensreddend geneesmiddel. Dit geneesmiddel wordt gebruikt om bloedklonters op te lossen die een acuut hartinfarct (myocardinfarct) of herseninfarct (beroerte) veroorzaken. Collen was tot zijn emeritaat in 2008 verbonden aan de Katholieke Universiteit Leuven (KU Leuven). Hij was oprichter van de "D. Collen Research Foundation", thans Life Sciences Research Partners, de Private Stichting Désiré Collen Stichting en de bedrijven Thromb-X NV en ThromboGenics NV (thans (nl)
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  • Désiré Collen (en)
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  • Désiré Collen (en)
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