Anthony Harkness (July 10, 1793 – May 10, 1858) was an American businessman, machinist, and inventor who was associated with the making of steam engines for water pumps, sugar mills, cotton mills, steamboats and railroad locomotives. He pioneered the railroad locomotive industry of Cincinnati, Ohio. He was successful in several business enterprises and became very wealthy. In his retirement, Harkness founded Glendale, Ohio, an upscale community just north of Cincinnati.