The 2022 Phillips 66 International Team Trials was held from April 26 to 30, 2022 in Greensboro, North Carolina at the Greensboro Aquatic Center. Contested swimming events were conducted in a 50-meter (long course) pool. The competition served as the selection meet for determining the swim team to represent the United States at the 2022 World Aquatics Championships, 2022 Junior Pan Pacific Swimming Championships, and 2022 Mel Zajac Junior International. It was held separate from the 2022 US National Championships.