The 2022 Ohio Bobcats football team represents Ohio University as a member of the East Division of the Mid-American Conference (MAC) in the 2022 NCAA Division I FBS football season. They are led by second-year head coach Tim Albin and play their home games at Peden Stadium in Athens, Ohio. They finished the regular season 9–3 and 7–1 in the MAC and won the MAC East for the first time since 2016. They lost to Toledo in the MAC Championship Game. Ohio will play Wyoming in the Arizona Bowl