The 2022 Big 12 Conference football season will be the 27th season of the Big 12 Conference football taking place during the 2022 NCAA Division I FBS football season. The season will begin on September 3 with non-conference play. Conference play will begin on September 24, 2022. The 2022 season will be the eleventh season for the Big 12 since the early 2010s conference realignment brought the Big 12 membership to its current form. It is also the final year in the ten team configuration, with BYU, Cincinnati, Houston and UCF entering before the 2023 season.