The 2020 McNeese State Cowboys football team represented the McNeese State University in the 2020–21 NCAA Division I FCS football season. The Cowboys played their home games at Cowboy Stadium in Lake Charles, Louisiana and competed in the Southland Conference. They were led by first-year head coach Frank Wilson. On August 13, McNeese State Athletic Department decided to postpone all fall sports with the intent to play in the spring. This decision canceled all games that were to be played from September through November 2020.