The 2018–19 Saint Louis Billikens women's basketball team represents the Saint Louis University during the 2018–19 NCAA Division I women's basketball season. The Billikens, led by seventh year head coach Lisa Stone, play their home games at the Chaifetz Arena and were members of the Atlantic 10 Conference. They finished the season 15–16, 9–7 in A-10 play to finish in sixth place. They advanced to the semifinals of the A-10 women's tournament where they lost to Duquesne.