The 2016–17 Louisville Cardinals men's basketball team represented the University of Louisville during the 2016–17 NCAA Division I men's basketball season. The Cardinals competed in the Atlantic Coast Conference and were coached by Rick Pitino, in his 16th and final season at Louisville. The team played its home games on Denny Crum Court at the KFC Yum! Center in downtown Louisville. They finished the season 25–9, 12–6 in ACC play to finish in a three-way tie for second place. They lost to Duke in the quarterfinals of the ACC tournament. They received an at-large bid to the NCAA tournament where they defeated Jacksonville State in the first round to advance to the second round where they lost to Michigan.