The 2015–16 Clemson Tigers women's basketball team will represent Clemson University during the 2015–16 college basketball season. The Tigers, are led by third year head coach Audra Smith. The Tigers, members of the Atlantic Coast Conference, will play their home games at Jervey Athletic Center due to renovations at Littlejohn Coliseum. They finished the season 4–26, 0–16 in ACC play to finish in last place. They lost in the first round of ACC women's tournament to Wake Forest.