The 2011–12 Xavier Musketeers men's basketball team represented Xavier University in the 2011–12 NCAA Divisions I Men's Basketball Season. Xavier was led by head coach Chris Mack in his third season at Xavier. The Musketeers competed in the Atlantic 10 Conference and played their home games at the Cintas Center. Xavier finished the season 23-13,10–6 in A-10 play to finish in tie for third place in conference. The Musketeers lost to St. Bonaventure in the championship of the A-10 tournament. Xavier received a #10 seed in the NCAA tournament. The Musketeers defeated Notre Dame and Lehigh to reach the Sweet Sixteen where they were defeated by Baylor.