The 2006 Conference USA men's basketball tournament was held March 8–11 at the FedExForum in Memphis, Tennessee. Top-seeded Memphis defeated UAB in the championship game, 57–46, to clinch their first Conference USA men's tournament championship. It would be the Tigers' first of seven C-USA titles in an eight-year period. The Tigers, in turn, received an automatic bid to the 2006 NCAA tournament. They were joined in the tournament by fellow C-USA member UAB, who earned an at-large bid.