The 1981 U.S. Women's Open was the 36th U.S. Women's Open, held July 23–26 at La Grange Country Club in LaGrange, Illinois, a suburb west of Chicago. Three strokes back after 54 holes, Pat Bradley shot a final round 66 (−6) to win her only U.S. Women's Open, one stroke ahead of runner-up Beth Daniel. It was the second of Bradley's six major titles. The course hosted the championship seven years earlier in 1974.