The 1952 United States Senate election in Arizona was held on November 4, 1952. Incumbent Democratic U.S. Senator and Senate Majority Leader Ernest McFarland ran for re-election to a third term, but was defeated by the Republican nominee and future candidate for President of the United States, Barry Goldwater. This election would mark the beginning of a decades-long stretch of Republican electoral success in Arizona; Republicans would go on to continuously hold at least one of the state's Senate seats until 2020, when Democrats took control of both Senate seats in Arizona.